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최동희 교수

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학력 및 경력

  • 산부인과 전문의
  • 연세대학교 의과대학 졸업
  • 연세대학교 의과대학 의학석사
  • 연세대학교 의과대학 의학박사
  • 연세대학교병원 산부인과 전공의
  • 차의과학대학교 차병원 산부인과장
  • 현 CHA 의과학대학교 분당차병원 난임센터 교수

학회 및 학술활동

  • 대한 산부인과학회 정회원
  • 대한 생식의학회 정회원
  • 대한 보조생식학회 정회원
  • 대한 보조생식학회 이사 역임

연구분야

  • 자궁내막유착증의 난소기능저하

최동희교수 인터뷰

  • 언론기사·영상
  • 논문
  1. Lee MH, Yoon JA, Kim HR, Kim YS, Lyu SW, Lee BS, Song H, Choi DH. Hyperandrogenic Milieu Dysregulates the Expression of Insulin Signaling Factors and Glucose Transporters in the Endometrium of Patients With Polycystic Ovary Syndrome. Reprod Sci. 2019 Mar 4:1933719119833487.
  2. Kim MS, Choi DH, Kwon H, Ahn E, Cho HY, Baek MJ, Shin JE, Moon MJ. Procedural and obstetric outcomes after embryo reduction vs fetal reduction in multifetal pregnancy. Ultrasound Obstet Gynecol. 2019 Feb;53(2):214-218.
  3. Kim H, Shin JE, Koo HS, Kwon H, Choi DH, Kim JH. Effect of Autologous Platelet-Rich Plasma Treatment on Refractory Thin Endometrium During the Frozen Embryo Transfer Cycle: A Pilot Study. Front Endocrinol (Lausanne). 2019 Feb 14;10:61.
  4. Shin JJ, Park KE, Choi YM, Kim HO, Choi DH, Lee WS, Cho JH. Early gonadotropin-releasing hormone antagonist protocol in women with polycystic ovary syndrome: A preliminary randomized trial. Clin Exp Reprod Med. 2018 Sep;45(3):135-142
  5. Na ED, Jung I, Choi DH, Kwon H, Heo SJ, Kim HC, Kang SH, Cho H. The risk factors of miscarriage and obstetrical outcomes of intrauterine normal pregnancy following heterotopic pregnancy management. Medicine (Baltimore). 2018 Sep;97(37):e12233.
  6. Kim HR, Cho KS, Kim E, Lee OH, Yoon H, Lee S, Moon S, Park M, Hong K, Na Y,Shin JE, Kwon H, Song H, Choi DH, Choi Y. Rapid expression of RASD1 is regulated by estrogen receptor-dependent intracellular signaling pathway in the mouse uterus. Mol Cell Endocrinol. 2017 May 5;446:32-39.
  7. Choi Y, Kim HR, Lim EJ, Park M, Yoon JA, Kim YS, Kim EK, Shin JE, Kim JH, Kwon H, Song H, Choi DH. Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF). PloS one. 2016; 11(6):e0157696.
  8. Kwon H, Choi DH, Kim EK. Absolute position versus relative position in embryo transfer: a randomized controlled trial. Reprod Biol Endocrinol. 2015 Jul 29;13:78.
  9. Kim HS, Lee BE, Jeon YJ, Rah H, Lee WS, Shin JE, Choi DH, Kim NK. Transcobalamin II (TCN2 67A>G and TCN2 776C>G) and transcobalamin II receptor (TCblR 1104C>T) polymorphisms in Korean patients with idiopathic recurrent spontaneous abortion. . Am J Reprod Immunol. 2014 Sep;72(3):337-46.
  10. Jung YW, Jeon YJ, Rah H, Kim JH, Shin JE, Choi DH, Cha SH, Kim NK. Geneticvariants in microRNA machinery genes are associated [corrected] with idiopathic recurrent pregnancy loss risk. PLoS One. 2014 Apr 25;9(4):e95803. doi: 10.1371/journal.pone.0095803. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e105743..
  11. Choi DH, Kwon H, Lee SD, Moon MJ, Yoo EG, Lee KH, Hong YK, Kim G. Testicular hypoplasia in monochorionic dizygous twin with confined blood chimerism. J Assist Reprod Genet. 2013 Nov;30(11):1487-91.
  12. Rah H, Jeon YJ, Lee BE, Kim JO, Shim SH, Lee WS, Choi DH, Kim JH, Kim NK.Association of polymorphisms in microRNA machinery genes (DROSHA, DICER1, RAN,and XPO5) with risk of idiopathic primary ovarian insufficiency in Korean women. Menopause. 2013 Oct;20(10):1067-73
  13. Jeon YJ, Kim JH, Lee BE, Rah H, Shin JE, Kang H, Choi DH, Yoon TK, Lee WS, Shim SH, Kim NK. Association between polymorphisms in the renin-angiotensin system genes and prevalence of spontaneously aborted fetuses. Am J Reprod Immunol. 2013 Sep; 70(3):238-45.
  14. Rah H, Jeon YJ, Shim SH, Cha SH, Choi DH, Kwon H, Kim JH, Shin JE, Kim NK.Association of miR-146aC>G, miR-196a2T>C, and miR-499A>G polymorphisms with risk of premature ovarian failure in Korean women. Reprod Sci. 2013 Jan;20(1):60-8.
  15. Kim JH, Jeon YJ, Lee BE, Kang H, Shin JE, Choi DH, Lee WS, Kim NK. Association of methionine synthase and thymidylate synthase genetic polymorphisms with idiopathic recurrent pregnancy loss. Fertil Steril. 2013; May;99(6):1674-80.
  16. Lee BE, Jeon YJ, Shin JE, Kim JH, Choi DH, Jung YW, Shim SH, Lee WS, Kim NK. Tumor necrosis factor-α gene polymorphisms in Korean patients with recurrent spontaneous abortion. Reprod Sci. 2013 Apr; 20(4):408-13.
  17. Rah H, Jeon YJ, Lee BE, Choi DH, Yoon TK, Lee WS, Kim NK. Association ofkinase insert domain-containing receptor (KDR) gene polymorphisms with idiopathic recurrent spontaneous abortion in Korean women. Fertil Steril. 2013 Mar 1;99(3):753-760.
  18. Rah H, Jeon YJ, Lee WS, Jung YW, Choi DH, Kwon H, Kim JH, Shin JE, Kim NK. Association of nitric oxide synthase gene polymorphisms (-786T>C, 4a4b, 894G>T) with primary ovarian insufficiency in Korean women. Maturitas. 2013 Feb; 74(2);160-5.
  19. Kim JH, Jeon YJ, Rah H, Lee BE, Choi DH, Lee WS, Kim NK. Tumor necrosis factor-alpha promoter polymorphisms are associated with idiopathic primary ovarian insufficiency in Korean women. Fertility and sterility. 2012 Nov; 98(5):1260-5.
  20. Rah H, Jeon YJ, Choi Y, Shim SH, Yoon TK, Choi DH, Cha SH, Kim NK. Association of methylenetetrahydrofolate reductase (MTHFR 677C>T) and thymidylate synthase (TSER and TS 1494del6) polymorphisms with premature ovarian failure in Korean women. Menopause. 2012 Nov;19(11):1260-6.
  21. Jeon YJ, Kim SY, Rah H, Choi DH, Cha SH, Yoon TK, Lee WS, Shim SH, Kim NK.Association of the miR-146aC>G, miR-149T>C, miR-196a2T>C, and miR-499A>G polymorphisms with risk of spontaneously aborted fetuses. Am J Reprod Immunol. 2012 Nov;68(5):408-17.
  22. Kim YS, Kwon H, Choi DH. Ruptured pyosalpinx following a fetal reduction procedure. Int J Gynaecol Obstet. 2012 Oct;119(1);84
  23. Rah H, Choi YS, Jeon YJ, Choi Y, Cha SH, Choi DH, Ko JJ, Shim SH, Kim NK.Solute Carrier Family 19, member 1 (SLC19A1) polymorphisms (-43T>C, 80G>A, and 696C>T), and haplotypes in idiopathic recurrent spontaneous abortion in a Korean population. Reprod Sci. 2012 May;19(5):513-9.
  24. Jeon YJ, Choi YS, Rah H, Kim SY, Choi DH, Cha SH, Shin JE, Shim SH, Lee WS, Kim NK. Association study of microRNA polymorphisms with risk of idiopathic recurrent spontaneous abortion in Korean women. Gene. 2012 Feb 25;494(2):168-73.
  25. Jeon YJ, Kim JH, Rah H, Kim SY, Yoon TK, Choi DH, Cha SH, Shim SH, Kim NK. Vascular endothelial growth factor gene polymorphisms in spontaneously aborted fetuses. Am J Repro Immunol. 2011 Dec;66(6):544-53.
  26. Choi YS, Kwon H, Kim JH, Shin JE, Choi Y, Yoon TK, Choi DH, Kim NK. Haplotype-based association of ACE I/D, AT1R 1166A>C, and AGT M235T polymorphisms in renin-angiotensin-aldosterone system genes in Korean women with idiopathic recurrent spontaneous abortions. Eur J Obstet Gynecol Reprod Biol. 2011 Oct;158(2):225-8.
  27. Choi DH, Kim EK, Kim KH, Lee KA, Kang DW, Kim HY, Bridges P, Ko C. Expression pattern of endothelin system components and localization of smooth muscle cells in the human pre-ovulatory follicle. Hum Reprod. 2011 May;26(5):1171-80
  28. 전영주, 최이슬, 나형철, 최영석, 윤태기, 최동희, 김남근. Genes and Genomics vol 33, No 3 223-228, 2011. The reduced folate carrier-1 (RFC1 696T-C) polymorphism is associated with spontaneously aborted embryos in Koreans.
  29. Yoon JE, Eunk iKim, Dong Hee Choi. The effect of oriental medicine therapy on results on In Vitro fertilization-Embryo transfer. J Korean Oriental Med 2010:31(2):71-77.
  30. Kwon H, Choi DH, Bae JH, Kim JH, Kim YS. mRNA expression pattern of insulin-like growth factor components of granulosa cells and cumulus cells in women with and without polycystic ovary syndrome according to oocyte maturity. Fertility and sterility vol 94, No 6, 2417-2420, 2010.
  31. 김은경, 김은하, 김은아, 권황, 홍재엽, 최동희. Successful Clinical Pregnancy and Livebirth was Achieved after Intracytoplasmic Sperm Injection in a Globozoospermic Patient: A Case Report. 대한생식의학회지 Vol 37, No 1, 83-88, 2010.
  32. 심성한, 윤태기, 차동현, 한원보, 최동희, 김남근. Endothelial Nitric Oxide Synthase (eNOS) Gene Polymorphisms in Spontaneously Aborted Embryos. Genes and Genomics vol 32, No 3, 283-285, 2010
  33. 최동희, 성세라, 박지은, 차동현, 윤태기, 심성한. Mutation analysis of EXT1 and EXT2 genes in a Korean family with multiple exostoses. Genes and Genomics vol 32, No 1, 19-21, 2010
  34. Choi DH, Lee WS, Won M, Park M, Park HO, Kim E, Lee KA, Bae J. The apolipoprotein A-I level is downregulated in the granulosa cells of patients with polycystic ovary syndrome and affects steroidogenesis. J Proteome Res. 2010 Sep 3;9(9):4329-36.
  35. Shin SJ, Lee HH, Cha SH, Kim JH, Shim SH, Choi DH, Kim NK. Endothelial nitricoxide synthase gene polymorphisms (-786T>C, 4a4b, 894G>T) and haplotypes in Korean patients with recurrent spontaneous abortion. Eur J Obstet Gynecol Reprod Biol. 2010 Sep;152(1):64-7
  36. Park HR, Moon MJ, Ahn EH, Baek MJ, Choi DH. Heterotopic quadruplet pregnancy: conservative management with ultrasonographically-guided KCl injection of corneal pregnancy and laparoscopic operation of tubal pregnancy. Fetal Diagn Ther. 2009;26(4):227-30.
  37. Choi DH, Kwon H, Kim YS, Kim JH. Intramural pregnancy associated withadenomyosis after in vitro fertilization and embryo transfer: a case report. J Reprod Med. 2009 Apr;54(4):255-8.
  38. Bae J, Choi DH, Kang MS, Cha SH, Oh D, Kim NK. Effect of methylenetetrahydrofolate reductase and thymidylate synthase enhancer region polymorphisms on the risk of idiopathic recurrent spontaneous abortion in a Korean population. Fertil Steril. 2009 Apr;91(4 Suppl):1560-2.
  39. Park HM, Shin SJ, Choi DH, Oh D, Lee S, Kim NK. Association between folate metabolism-related gene polymorphisms and methylation of p16(INK4A) and hMLH1 genes in spontaneously aborted embryos with normal chromosomal integrity. Fertil Steril. 2008 Nov;90(5):1605-10.
  40. 박혜미, 김혜진, 신승주, 차선희, 최동희, 고정재, 오도연, 김남근. Association of the Folate Metabolism-related Gene Polymorphisms in Spontaneously Aborted Embryos with Abnormal Chromosomal Integrity. 한국유전학회지 Vol 29, No 3, 389-393, 2007.
  41. Bae J, Shin SJ, Cha SH, Choi DH, Lee S, Kim NK. Prevalent genotypes ofmethylenetetrahydrofolate reductase (MTHFR C677T and A1298C) in spontaneously aborted embryos. Fertil Steril. 2007 Feb;87(2):351-5.
  42. Kim NK, Choi YK, Kang MS, Choi DH, Cha SH, An MO, Lee S, Jeung M, Ko JJ, Oh D. Influence of combined methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase enhancer region (TSER) polymorphisms to plasma homocysteine levels in Korean patients with recurrent spontaneous abortion. Thromb Res.2006;117(6):653-8
  43. Yoon SJ, Kim KH, Chung HM, Choi DH, Lee WS, Cha KY, Lee KA. Gene expression profiling of early follicular development in primordial, primary, and secondary follicles. Fertil Steril. 2006 Jan;85(1):193-203.
  44. 강진희, 박이석, 최동희, 이숙환, 권황, 김유신, 심수진, 오영란, 양옥현, 석현하. IVF-ET후 발생한 동시 양측난관임신 1례. 대한산부인과 Vol 48, No 11, 2735~2738, 2005.
  45. Cha KY, Chung HM, Lee DR, Kwon H, Chung MK, Park LS, Choi DH, Yoon TK. Obstetric outcome of patients with polycystic ovary syndrome treated by in vitro maturation and in vitro fertilization-embryo transfer. Fertil Steril. 2005 May;83(5):1461-5.
  46. Jeong HJ, Cho SW, Kim HA, Lee SH, Cho JH, Choi DH, Kwon H, Cha WT, Han JE, Cha KY. G769A variation of inhibin alpha-gene in korean women with premature ovarian failure. Yonsei Med J. 2004 Jun 30;45(3):479-82.
  47. Yoon SJ, Choi DH, Lee WS, Cha KY, Kim SN, Lee KA. A molecular basis forembryo apposition at the luminal epithelium. Mol Cell Endocrinol. 2004 Apr 30;219(1-2):95-104.
  48. Cha KY, Chung HM, Lim JM, Ko JJ, Han SY, Choi DH, Yoon TK. Freezing immature oocytes. Mol Cell Endocrinol. 2000 Nov 27;169(1-2):43-7. Review.
  49. Choi DH, Chung HM, Lim JM, Ko JJ, Yoon TK, Cha KY. Pregnancy and delivery of healthy infants developed from vitrified blastocysts in an IVF-ET program. Fertil Steril. 2000 Oct;74(4):838-9.
  50. Cha KY, Han SY, Chung HM, Choi DH, Lim JM, Lee WS, Ko JJ, Yoon TK. Pregnancies and deliveries after in vitro maturation culture followed by in vitro fertilization and embryo transfer without stimulation in women with polycystic ovary syndrome. Fertil Steril. 2000 May;73(5):978-83.
  51. Chung HM, Hong SW, Lim JM, Lee SH, Cha WT, Ko JJ, Han SY, Choi DH, Cha KY. In vitro blastocyst formation of human oocytes obtained from unstimulated and stimulated cycles after vitrification at various maturational stages. Fertil Steril. 2000 Mar;73(3):545-51.
  52. 남윤성, 이숙환, 최동희, 윤태기, 차광열. Pergolide 에 반응한 Bromocriprine저항성 고프로락틴혈증 1례. 대한불임학회지 제26권 제2호 287-292 1998.
  53. 남윤성, 한세열, 최동희, 윤태기, 차광열. C 단백질 부족증과 관련된 항인지질 증후군1례. 대한불임학회지 제26권 제1호 123-126 1998.
  54. 남윤성, 한세열, 최동희, 윤태기, 차광열. 항인지질증후군과 관련된 반복자연유산 1례. 대한불임학회지 제25권 제3호 277-280 1998.
  55. 이경아, 한세열, 최동희, 이우식, 윤태기, 차광열. 체외수정 환자에서 난자회수 2일째의 자궁내막의 Pinopode의 발달. 대한불임학회지 제25권 제1호 51-28 1998.
  56. 오종훈, 엄기붕, 최동희, 정미경, 한세열, 차광열, 정길생. 항정자항체가 일반적 체외수정 방법 및 정자직접주입법(ICSI)에 미치는 영향에 관한 연구. 대한불임학회지 제24권 제3호 385-392 1997
  57. 김현주, 김영찬, 엄기붕, 오종훈, 이우식, 한세열, 최동희, 윤태기, 차광열. 폐색성 무정자증환자의 치료로써 미세적부고환 정자흡입술(MESA)및 정자직접주입법(ICSI) 의 효과. 대한불임학회지 제22권 제2호 143-148 1995.
  58. 박성은, 최동희, 노환철, 고정재, 박종영, 차광열. 불임환자에 있어서 Partial Zona Dissection(PZD)에 의한 임상적인 결과. 대한불임학회지 제20권 제1호 37-44 1993.
  59. Cha KY, Koo JJ, Ko JJ, Choi DH, Han SY, Yoon TK. Pregnancy after in vitro fertilization of human follicular oocytes collected from nonstimulated cycles, their culture in vitro and their transfer in a donor oocyte program. Fertil Steril. 1991 Jan;55(1):109-13